"It's an honor to see you in this state," Itachi Uchiha said, a note of respect in his voice. After a brief pause, he whispered to Kisame beside him, "It seems that Lady Tsunade can only be left to you. Don't get carried away. If you can't win, try to prolong the battle. Her self-healing technique won't last long."

Kisame nodded. "Understood, Itachi-san." He always heeded Itachi's suggestions. After a long period of working together, Kisame knew one thing clearly: Itachi's combat intelligence was unmatched.

After a moment of thought, Kisame clenched Samehada in his hand and spoke softly to Tsunade. "Lady Tsunade, our fighting style is rather rough. Let's move to a deserted place to avoid interfering with them."

Tsunade didn't object, as that was exactly her intention. The two moved swiftly and soon arrived at a desolate canyon. The sky above was gray, as if a massive hole had been torn in it, and cold rain poured down relentlessly. The rain gathered into muddy streams, rushing wildly along the steep, rugged canyon walls, roaring as they surged at the bottom of the valley.

"Hahahaha, hahahahahaha…" Kisame's laughter echoed through the canyon. "Even the world is helping me. I have the best timing and location for this battle."

Tsunade frowned, her fists clenched at her sides. The air was thick with the strong smell of damp earth, and a cold, wet chill seeped into her bones. Every breath felt like an ice blade slicing through her throat.

Seeing Tsunade's grim expression, Kisame sneered. "What? Feeling the pressure already? Why not just surrender and hand Orochimaru over to me? Then you won't have to suffer any longer."

"How dare you! Shut your mouth!" A violent rage, mixed with icy murderous intent, surged through Tsunade like ignited volcanic lava. "I swear I will smash you like a watermelon.!"

Her last word still echoed in the rain as Tsunade's figure vanished from the rock where she stood. All that remained was a deep pit, covered with spider-web-like cracks, trampled into the ground by raw, violent force, and a circle of white rain mist blown away by her movement.

Tsunade's speed was blinding. As she tore through the rain curtain, she left behind a blurry afterimage, almost impossible to capture with the naked eye. She carried an overwhelming, terrifying momentum, heading straight for Kisame.

"So fast!" Kisame's tiny pupils contracted sharply. He hadn't expected that this Sannin, renowned for her extraordinary strength and medical skills, possessed such astonishing speed and explosive power. Could it be that her current state is also some form of sage mode?

Kisame didn't dare underestimate her. He could clearly feel the violent nature of this force and chose not to take it head-on. Instead, at the critical moment, his body slid to the side. At the same time, Samehada on his shoulder seemed to awaken with its own consciousness, letting out an excited roar. The massive blade slashed across Tsunade's path with a dull sound of breaking through the air.

"Too slow! Is this the extent of your strength?" Tsunade's taunt and attack arrived before Samehada could even whip up a strong wind. Her body displayed a flexibility and coordination unique to her in the high-speed sprint. She swung her muscular right fist in an incredible arc, striking Kisame's wrist with devastating force.

"Argh!" With a pained wail from Kisame, his right hand was shattered by Tsunade's monstrous strength. The fragments of flesh and bone on the ground were quickly washed away by the torrential rain.